Handedness and language learning disability differentially distribute in progressive aphasia variants
نویسندگان
چکیده
منابع مشابه
Handedness and language learning disability differentially distribute in progressive aphasia variants.
Primary progressive aphasia is a neurodegenerative clinical syndrome that presents in adulthood with an isolated, progressive language disorder. Three main clinical/anatomical variants have been described, each associated with distinctive pathology. A high frequency of neurodevelopmental learning disability in primary progressive aphasia has been reported. Because the disorder is heterogeneous ...
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BACKGROUND Although risk factors for Alzheimer disease have been well studied, much less is known about risk factors for primary progressive aphasia (PPA). OBJECTIVE To demonstrate that learning disabilities (LDs) are more common in patients with PPA and their first-degree family members. DESIGN, SETTING, AND PATIENTS Self-report endorsement of an individual and family history of an LD in a...
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We performed a comprehensive cognitive, neuroimaging, and genetic study of 31 patients with primary progressive aphasia (PPA), a decline in language functions that remains isolated for at least 2 years. Detailed speech and language evaluation was used to identify three different clinical variants: nonfluent progressive aphasia (NFPA; n = 11), semantic dementia (SD; n = 10), and a third variant ...
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ژورنال
عنوان ژورنال: Brain
سال: 2013
ISSN: 1460-2156,0006-8950
DOI: 10.1093/brain/awt242